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KMID : 0882419930450050676
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Korean Journal of Medicine
1993 Volume.45 No. 5 p.676 ~ p.680
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Secondary Hemochromatosis in a Long Term Hemodialysis Patients
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신원호
심대석/류경렬/김건용/김건호/이옥재/황일용
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Abstract
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econdary hemochromatosis is primarily a consequence of the treatment of the anemia of long term hemodialysis patients with frequent blood transfusions, seldom a result of oral or parentral iron therapy. Clinically, iron overload may be a serious
problem
for some maintenance hemodialysis patients and may be manifested by organ dysfunctions. Diagnosis of
iron overload can be established by serum ferritin determination, liver biopsy or bone marrow
examination, which correlates closely with total body iron stores. It is important to early
detect thr iron overload and to ristrict blood transfusions or iron therapy in these patients.
We present secondary hemochromatosis in a long term hemodialysis patients with 140
pints blood transfusions for 5 years, confirmed by serum ferritin level, HLA (human leukocyte
antigen) test and liver biopsy. We are treating this patient with recombinant human
erythropoietin (EPO) in order to reduce the frequency of blood transfusions.
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